Campbell Neurosciences, inc.

Committed to establishing a biological basis for diagnosis and treatment of suicide and its causes, including Schizophrenia and other mental health disorders, thereby eliminating the stigma of the disease.

Diagnostics

Campbell Score™ is an analysis of what is happening in blood. Proprietary algorithm utilizing already available blood tests to establish patients at risk of suicide.

Regenerative Psychiatry

CampbellCell™ stimulates immune modulation and production of the cytokine brain derived neurotrophic factors (BDNF).

Nutraceutical Adjuvants

The potent generation of T regulatory cells by the combination of QuadraMune™ and Minocycline suggests potent generation of T regulatory cells with therapeutic effects.

Campbell Score

  1. Analysis of what is happening in blood.
    Proprietary algorithm utilizing already available blood tests to establish patients at risk of suicide.
  2. Analysis of what is happening in brain. 
    Brain produces very small particles called exosomes that we can isolate, and they tell us how much inflammation is happening specifically in the brain. 
  3. Analysis of what is happening in the gut.
    Analysis of the microbiome in gut suggests overall inflammation in body
  4. Analysis of suicide associated gene. 
    Several gene polymorphisms have been shown to be associated with suicide.

CampbellCell

Our universal donor stem cells have been shown to reduce symptoms of schizophrenia in an animal model through stimulation of immune modulation and production of the cytokine brain derived neurotrophic factors (BDNF).

In a series of experiments, it was demonstrated that CampbellCell administration resulted in upregulated production of the cytokine interleukin-4, which was needed to reduce the inflammatory cytokine interleukin-17 and to suppress schizophrenia development.

NeuroLeukin

Neuroleukin is a combination of the patient’s own platelet rich plasma, generated in a proprietary manner, combined with NanoStilbene, a patented delivery method of the nutraceutical ingredient pterostilbene.  The combination is administered intranasally by the patient at once a day for a week.  The procedure involves the patient coming to the doctor’s office, having a small amount of blood (20 ml) removed, and the first dose of the product is given to the patient at the doctor’s office, while subsequent doses are frozen and the patient self-administers. Evaluation of efficacy of the intervention is performed using standard psychological tools, as well as in some patients the Campbell Score™.  

NarcoStem

An umbilical cord blood derived biologic demonstrated to possess positive animal data in preclinical models of addiction and drug induced brain damaged. This demonstration that BDNF mediates therapeutic activities of NarcoStem™ helps accelerate the timeline for clinical translation of this inhalable therapeutic. BDNF is considered a “master molecule” in controlling brain function and has been reported by numerous groups to associate with efficacy of anti-depressants, as well as the ability to overcome addictive tendencies. Accordingly, preliminary data by the Company suggests that administration of NarcoStem™ can directly stimulate the brain to produce its own BDNF.